The Doudna Lab

Exploring molecular mechanisms of RNA-mediated gene regulation

Collecting X-ray diffraction data at the Advanced Light Source Ancestral cGAS homologs reveal evolution of innate immune signaling Operating the ITC in our lab in Stanley Hall Macromolecular crystallography facilitated by robotics at UC Berkeley Analyzing RNA samples using gel electrophoresis in the lab

Recent publications

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.

Jiang F, Taylor DW, Chen JS, Kornfeld JE, Zhou K, Thompson AJ, Nogales E, Doudna JA
Science 2016 Jan 14. pii: aad8282.

Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering.

Wright AV, Nuñez JK, Doudna JA
Cell 2016 Jan 14;164(1-2):29-44.

Tunable protein synthesis by transcript isoforms in human cells.

Floor SN, Doudna JA
eLife 2016 Jan 6;5. pii: e10921

Genome-editing revolution: My whirlwind year with CRISPR.

Doudna JA
Nature 2015 Dec 24;528(7583):469-71

Genome editing: the end of the beginning.

Doudna JA, Gersbach CA
Genome Biol 2015 Dec 23;16(1):292

Analog sensitive chemical inhibition of the DEAD-box protein DDX3.

Floor SN, Barkovich KJ, Condon KJ, Shokat KM, Doudna JA
Protein Sci 2015 Dec 9;


Yun Bai leaves for her new faculty position at ShanghaiTech, congrats Yun!

Jennifer Doudna was on the PBS NewsHour

Steve Lin leaves for his new faculty position at Academica Sinica, congrats Steve!

Jorge passes his quals!

Photos and presentations from the NAM Human Gene-Editing Initiative