SRP Structure

Click on the Image to see the full sized view

1.5-Å crystal structure of the RNA-protein core of the signal recognition particle, responsible for signal peptide recognition of proteins targeted for secretion or membrane insertion.

References:

• Batey, R.T., Sagar, M.B. and Doudna, J.A. (2001) Structural and energetic analysis of nucleic acid recognition by a universally conserved protein from the signal recognition particle.J. Mol. Biol.307,229-246. (840KB PDF)
• Batey, R.T., Rambo, R.P., Lucast, L., Rha, B. and Doudna, J.A. (2000)Crystal structure of the ribonucleoprotein core of the signal recognition particle.Science287, 1232-1239.

© 2000 The American Association for the Advancement of Science